Non-functional IgG transcripts in a case of hyper- IgM syndrome similar to type 4
نویسندگان
چکیده
منابع مشابه
Biased immunoglobulin G (IgG) subclass production in a case of hyper-IgM syndrome.
Hyper-immunoglobulin M (IgM) syndrome (HIGM) is a rare heterogeneous primary immune deficiency. We describe a patient with HIGM characterized by skewed production of serum IgG subclasses and normal somatic hypermutation. This case may represent a subgroup of HIGM type 4 that is characterized by a biased switching to the V-region proximal constant regions.
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